http://www.biospace.comBioSpace RSS GeneratorTue, 18 Jun 2013 16:24:56 GMT20http://rss.biospace.com/images/BSPLogo.gifhttp://www.BioSpace.com/news.aspx?SectionId=1Copyright (C) 2011http://www.businesswire.com/portal/site/biospace/index.jsp?ndmViewId=news_view&newsId=20111115005264&newsLang=enCAMBRIDGE, Mass.--(BUSINESS WIRE)--Knome Inc., the human genome interpretation company, today announced the release of knomeBASE, an informatics service that transforms raw sequence data from human genomes into a format optimized for interpretation by geneticists seeking to understand the basis of human disease or drug response. Designed to enable the comparison and interpretation of large numbers...Tue, 15 Nov 2011 12:00:00 AM GMThttp://www.biospace.com/news_story.aspx?StoryID=148739&full=1<p>REYKJAVIK, Iceland, July 6 /PRNewswire-FirstCall/ -- Scientists at deCODE genetics and academic colleagues from Europe and the United States today present in the journal Nature Genetics the discovery of common genetic risk factors for basal cell carcinoma (BCC) that affect people with fair and dark complexions alike. deCODE had previously discovered five common single-letter variants in the sequence...Mon, 06 Jul 2009 12:00:00 AM GMThttp://www.biospace.com/news_story.aspx?StoryID=148204&full=1<p>febit Technology Enables the Conversion of New Sequence Data into Biochips for Gene Expression Profiling and Sequence Capture for Next-Generation Sequencing Within Days</p><p></p><p>LEXINGTON, Mass. and HEIDELBERG, Germany, June 29 /PRNewswire/ -- febit holding gmbh announced today the launch of the first biochip on the market covering the newly published whole mouse genome. The biochip from febit...Tue, 30 Jun 2009 12:00:00 AM GMThttp://www.bloomberg.com/apps/news?pid=20601124&sid=aU0NQ_VoBCOI&refer=homeNov. 20 (Bloomberg) -- A new technique could map DNA sequences 30,000 times faster than current methods, accelerating researchers' work to unravel the complex mutations that cause human disease.Fri, 21 Nov 2008 12:00:00 AM GMThttp://www.reuters.com/article/scienceNews/idUSTRE4A49CF20081105HONG KONG (Reuters) - Scientists have sequenced the entire gene maps of two men, one Chinese and the other African, for a fraction of the price that such exercises used to cost.Thu, 06 Nov 2008 12:00:00 AM GMThttp://www.biospace.com/news_story.aspx?StoryID=111084&full=1<b><img src"http://enewsletters.biospace.com/images/columnists/suvarnabhatt.jpg" width"100" height"123" hspace"5" vspace"3" align"left" />Bay Area DNA Decoding Company, 23andMe Gets More Personal </b><br>By <a href"http://www.biospace.com/community/persona.aspx?plckPersonaPagePersonaProfile&plckUserId482383&bioId482383&sidsitelife.biospace.com"><b>Suvarna Bhatt, Feature Editor</b></a>...Fri, 26 Sep 2008 12:00:00 AM GMThttp://washington.bizjournals.com/washington/stories/2008/08/04/story1.html?b=1217822400%5E1677876A Madison, Wis., biotech is moving to Montgomery County and expects to swell to seven times its size by this time next year. OpGen Inc., which has devised a way to more fully map a microorganisms genome, is shifting its home base from the Midwest to the longtime mecca of genomic research, where human DNA was first blueprinted.Mon, 04 Aug 2008 12:00:00 AM GMThttp://www.sciencedaily.com/releases/2008/07/080707135615.htmScienceDaily Researchers from Harvard Medical School and Brandeis University have successfully completed a full-genome RNAi screen in neurons, showing what types of genes are necessary for brain development.Wed, 09 Jul 2008 12:00:00 AM GMThttp://www.sciencedaily.com/releases/2008/06/080602214135.htmScienceDaily As the cost of sequencing a single human genome drops rapidly, with one company predicting a price of $100 per person in five years, soon the only reason not to look at your "personal genome" will be fear of what bad news lies in your genes.Tue, 03 Jun 2008 12:00:00 AM GMThttp://www.sciencedaily.com/releases/2008/05/080515120802.htmScienceDaily A large genetic study in mice has identified hundreds of genes involved in the development of cancer by examining the DNA of more than 500 lymphomas to find the cancer causing mutations.Tue, 20 May 2008 12:00:00 AM GMThttp://www.ns.umich.edu/htdocs/releases/story.php?id=6536University of Michigan -- The mouse is a stalwart stand-in for humans in medical research, thanks to genomes that are 85 percent identical. But identical genes may behave differently in mouse and man, a study by University of Michigan evolutionary biologists Ben-Yang Liao and Jianzhi Zhang reveals.Fri, 16 May 2008 12:00:00 AM GMThttp://www.newscientist.com/article/mg19726482.900-genome-is-a-snip-at-60000.htmlNew Scientist -- WHEN the cost of sequencing a human genome gets down to the price of a family car, then the era of personalised genomics will truly be upon us. This was the prediction from James Watson, co-discoverer of the structure of DNA, in an interview with New Scientist (20 October 2007, p 58) last year. Well, it's getting close. Last week, Applied Biosystems of Foster City, California, announced...Tue, 25 Mar 2008 12:00:00 AM GMThttp://www.eurekalert.org/pub_releases/2008-03/uu-fct031708.phpEurekAlert -- Fungi do not have sexes, just so-called mating types. A new study being published today in the prestigious journal PLoS shows that there are great similarities between the parts of DNA that determine the sex of plants and animals and the parts of DNA that determine mating types in certain fungi. This makes fungi interesting as new model organisms in studies of the evolutionary development...Tue, 18 Mar 2008 12:00:00 AM GMThttp://www.eurekalert.org/pub_releases/2008-02/cuc-prc020408.phpITHACA, N.Y. - Out of chaos, control: Cornell University molecular biologists have discovered how a protein called PARP-1 binds to genes and regulates their expression across the human genome. Knowing where PARP-1 is located and how it works may allow scientists to target this protein while battling common human diseases. Their research is in a study published today (Feb.8, 2008) in the journal Science...Fri, 08 Feb 2008 12:00:00 AM GMThttp://www.businesswire.com/portal/site/biospace/index.jsp?epi-content=GENERIC&newsId=20080206006314&ndmHsc=v2*A1201784400000*B1202427774000*DgroupByDate*G2*J2*N1000122&newsLang=en&beanID=1229976837&viewID=news_viewSAN DIEGO--(BUSINESS WIRE)--Illumina, Inc. (NASDAQ:ILMN) today announced that scientists at the Company have sequenced the genome of an anonymous African male (Yoruba from Ibadan, Nigeria), using the Genome Analyzer. Sequencing of this HapMap sample was conducted internally and marks the first human genome sequence generated exclusively with paired reads of 35 to 50 bases in length. Leveraging recent...Thu, 07 Feb 2008 12:00:00 AM GMThttp://www.smh.com.au/news/science/three-parents-produce-one-embryo/2008/02/05/1202090420956.htmlLONDON - British scientists have created human embryos containing DNA from two women and one man, a procedure that could potentially prevent conditions including epilepsy, diabetes and heart failure. Though the preliminary research has raised concerns about the possibility of genetically modified babies, the scientists say that the embryos are still only primarily the product of one man and one woman...Tue, 05 Feb 2008 12:00:00 AM GMThttp://www.sciencedaily.com/releases/2008/01/080116115406.htmHuman evolution has created enhancements in key genes connected to the p53 regulatory network -- the so-called guardian of the genome -- by creating additional safeguards in human genes to boost the network's ability to guard against DNA damage that could cause cancer or a variety of genetic diseases, an international team of scientists led by Cincinnati Children's Hospital Medical Center writes in...Fri, 18 Jan 2008 12:00:00 AM GMThttp://www.eurekalert.org/pub_releases/2008-01/joci-igd122607.phpThere are two major types of inflammatory bowel disease (IBD), Crohn disease (CD) and ulcerative colitis (UC). Conflicting reports have indicated that the soluble factor IL-22 can have both IBD promoting and IBD controlling effects. But now, Atsushi Mizoguchi and colleagues at Massachusetts General Hospital, Boston, have established that IL-22 ameliorates disease in a mouse model of UC.Thu, 03 Jan 2008 12:00:00 AM GMThttp://researchnews.osu.edu/archive/firecancr.htmCOLUMBUS, Ohio Researchers here have figured out a way to use a firefly gene to let them see just how effective a new drug combination actually is against some forms of cancer and its serious complication.Wed, 02 Jan 2008 12:00:00 AM GMThttp://www.eurekalert.org/pub_releases/2008-01/asoc-aoc122007.phpAlexandria, VAIsraeli investigators have found that Ashkenazi Jewish women with ovarian cancer who have mutations in the BRCA1 or BRCA2 genes lived significantly longer than Ashkenazi Jewish ovarian cancer patients without these mutations. After up to nine years of follow-up, BRCA1/2 mutation carriers were 28 percent less likely to die from the disease, even though women with the BRCA mutations are...Wed, 02 Jan 2008 12:00:00 AM GMThttp://www.eurekalert.org/pub_releases/2008-01/mgh-gvm122107.phpA particular gene variation appears to significantly increase the risk that individuals with cirrhosis of the liver will go on to develop hepatocellular carcinoma (HCC), a liver tumor that is the third leading cause of cancer death. In the January 2 Journal of the American Medical Association, researchers from Massachusetts General Hospital (MGH) Cancer Center and colleagues in France describe finding...Wed, 02 Jan 2008 12:00:00 AM GMThttp://www.newscientist.com/article/mg19626344.600-painkiller-gene-turned-off-in-mice.htmlWe experience chilli peppers as hot because they activate an enzyme called c-Kit. It now seems that getting rid of c-Kit increases pain tolerance in mice, while stimulating it lowers the level at which heat becomes painful. This could lead to the development of a new class of painkillers that work by blocking the enzyme.Wed, 19 Dec 2007 12:00:00 AM GMThttp://www.hopkinsmedicine.org/Press_releases/2007/12_11_07.htmlSurrounding the small islands of genes within the human genome is a vast sea of mysterious DNA. While most of this non-coding DNA is junk, some of it is used to help genes turn on and off. As reported online this week in Genome Research, Hopkins researchers have now found that this latter portion, which is known as regulatory DNA and contributes to inherited diseases like Parkinsons or mental disorders...Tue, 18 Dec 2007 12:00:00 AM GMThttp://news.bbc.co.uk/2/hi/health/7146860.stmScientists say they have found two genetic mutations which could triple the risk of developing bowel cancer.Earlier this year, a study funded by Cancer Research UK found the first section of the human genome linked to bowel cancer. Mon, 17 Dec 2007 12:00:00 AM GMThttp://www.umassmed.edu/Content.aspx?id=45744WORCESTER, Mass. Can a tiny winged insects salivary glands really tell us about processes relevant to human disease? Yes, according to a new study by researchers at the University of Massachusetts Medical School (UMMS), who gained new insights into autophagya cellular degradation process associated with a form of programmed cell deathby studying the salivary gland cells of the fruit fly. Mon, 17 Dec 2007 12:00:00 AM GMThttp://www.eurekalert.org/pub_releases/2007-12/l-suc121307.phpPROVIDENCE, R.I. A new study by researchers at Hasbro Childrens Hospital, the pediatric division of Rhode Island Hospital, and Mount Sinai Hospital, New York, offers new insight into the role that the cystic fibrosis gene plays in the development of gastrointestinal disease.The cystic fibrosis transmembrane conductance regulator (CFTR) gene codes for a protein also known as CFTR. Mutations of...Fri, 14 Dec 2007 12:00:00 AM GMThttp://today.uci.edu/news/release_detail.asp?key=1705University of California, Irvine researchers have identified the chemical switch that triggers the genetic mechanism regulating our internal body clock.The finding, which uncovers the most specific information about the bodys circadian rhythms to date, identifies a precise target for new pharmaceuticals that can treat sleep disorders and a host of related ailments. The study appears in the Dec...Thu, 13 Dec 2007 12:00:00 AM GMThttp://technology.newscientist.com/article/mg19626335.800-silenced-genes-can-no-longer-stay-hidden.htmlA program that teaches itself to recognise the DNA patterns in silenced genes could help us better understand many diseases.Mammals, including us, have two copies of each gene: one from the mother and one from the father. Normally, both are expressed, but occasionally one is imprinted, or silenced, which gives the other the deciding role. If this active gene is a mutation that would otherwise have...Thu, 13 Dec 2007 12:00:00 AM GMThttp://www.tgen.org/news/index.cfm?pageid=57&newsid=1104PHOENIX, AZ, DECEMBER 11, 2007-Results from two genome-wide association studies have identified a genetic variant of the DAB2IP gene that is associated with the risk of aggressive prostate cancer. Research teams from the Translational Genomics Research Institute (TGen), Wake Forest University School of Medicine, the Karolinska Institute in Stockholm, Sweden, and Johns Hopkins Medical Institutions made...Wed, 12 Dec 2007 12:00:00 AM GMThttps://my.mcg.edu/portal/page/portal/News/archive/2007/Genes%20identified%20that%20protect%20against%20heart%20damage%20from%20chemA series of genes that protect cells from the powerful, common chemotherapeutic agent doxorubicin has been identified by researchers working to understand how the drug also can destroy the heart."We found a series of genes that are very important for cell survival in the face of doxorubicin, says Dr. Hernan Flores-Rozas, cancer researcher at the Medical College of Georgia Cancer Center. At the...Wed, 12 Dec 2007 12:00:00 AM GMThttp://www.nih.gov/news/pr/dec2007/nci-10.htmIn laboratory experiments using budding yeast, the same type used in baking and brewing, scientists at the National Cancer Institute (NCI), part of the National Institutes of Health, developed a new approach to determine the location of unrepaired breaks in DNA. This new approach should better inform research as unrepaired DNA damage often underlies the development of cancer. The research findings...Tue, 11 Dec 2007 12:00:00 AM GMThttp://www.reuters.com/article/healthNews/idUSN0935659520071209NEW YORK (Dec. 9, 2007) An international team of researchers led by Columbia University Medical Centers Herbert Irving Comprehensive Cancer Center and Swedens Lund University has, for the first time, revealed how mutations in the BRCA1 gene lead to breast cancer. Findings show that one way BRCA1 mutations cause cancer is by knocking out a powerful tumor suppressor gene known as PTEN.Mon, 10 Dec 2007 12:00:00 AM GMThttp://www.nih.gov/news/pr/dec2007/niaaa-05.htmA variant of a gene involved in communication among brain cells has a direct influence on alcohol consumption in mice, according to a new study by scientists supported by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health (NIH), and the U.S. Army.Thu, 06 Dec 2007 12:00:00 AM GMThttp://www.news.wisc.edu/14507Experts have been warning for years that foods loaded with high-fructose corn syrup and other processed carbohydrates are making us fatter. Now, a UW-Madison study has uncovered the genetic basis for why this is so.Wed, 05 Dec 2007 12:00:00 AM GMThttp://www.fastcompany.com/magazine/121/are-there-holes-in-my-genes_Printer_Friendly.htmlThis year has been tough for my family. First, my uncle was diagnosed with sarcoidosis, an incurable inflammatory disease. Then my sister needed surgery to remove precancerous tissue from her cervix. The hardest blow came this summer, when my cousin--just 28, and always healthier than anyone else in the family--was diagnosed with aggressive breast cancer.Living on the other side of the world-...Wed, 05 Dec 2007 12:00:00 AM GMThttp://www.eurekalert.org/pub_releases/2007-12/yu-nie112907.phpNew Haven, Conn.Boosting an exercise-related gene in the brain works as a powerful anti-depressant in micea finding that could lead to a new anti-depressant drug target, according to a Yale School of Medicine report in Nature Medicine.The VGF exercise-related gene and target for drug development could be even better than chemical antidepressants because it is already present in the brain, said...Mon, 03 Dec 2007 12:00:00 AM GMThttp://www.wellcome.ac.uk/doc_WTX042169.htmlWellcome Trust researchers have identified a key gene involved in the disease lupus, which affects around 50 000 people in the UK, most of them women. The lead researcher behind the study has called for more patients to volunteer DNA samples to enable them to further study the underlying causes of the disease.Mon, 03 Dec 2007 12:00:00 AM GMThttp://www.dukemednews.org/news/article.php?id=10189DURHAM, NC Scientists at Duke University have created the first map of imprinted genes throughout the human genome, and they say a modern-day Rosetta stone a form of artificial intelligence called machine learning was the key to their success.The study revealed four times as many imprinted genes as had been previously identified and is featured on the cover of the December 3 issue of Genome...Fri, 30 Nov 2007 12:00:00 AM GMThttp://www.wi.mit.edu/news/archives/2007/ah_1129.htmlCAMBRIDGE, Mass. (November 29, 2007) Crossovers and double-strand DNA breaks do not occur randomly on yeast chromosomes during meiosis, but are greatly influenced by the proximity of the chromosomes telomere, according to research in the laboratory of Whitehead Fellow Andreas Hochwagen. This work may lead to a better understanding of developmental chromosome abnormalities and birth defects.Fri, 30 Nov 2007 12:00:00 AM GMThttp://www.newscientist.com/article/mg19626324.100-intelligence-genes-reveal-their-complexity.htmlSomething as subtle and complex as intelligence was never going to be pinned on just a handful of genes, as a huge trawl across the human genome seems to confirm. Although it did turn up hundreds of genes that make a contribution, their individual effects are so small that for the most part they are barely detectable. This does not mean, however, that intelligence is not inherited.Fri, 30 Nov 2007 12:00:00 AM GMThttp://www.reuters.com/article/healthNews/idUSKRA77844120071127NEW YORK (Reuters Health) - Mutations in the BRCA1 and BRCA2 genes that increase the risk of breast cancer for women also do the same in men.Men can develop breast cancer, although they account for only about 1 percent of breast cancer cases. Previous studies have shown that men who carry mutations in the BRCA2 gene are at greater risk of developing breast cancer than men in the general population...Wed, 28 Nov 2007 12:00:00 AM GMThttp://www.med.umich.edu/opm/newspage/2007/bortezomib.htmANN ARBOR, MI University of Michigan Comprehensive Cancer Center researchers have discovered that bortezomib, a promising cancer drug, is able to strike a blow against melanoma tumor cells by revving up the action of a cancer-promoting gene.Mon, 26 Nov 2007 12:00:00 AM GMThttp://www.sciencedaily.com/releases/2007/11/071114151513.htmResearchers are closer to understanding why humans differ so greatly from chimpanzees in the way they look, behave, think, and fight off disease, despite having genes that are nearly 99% identical. Innovative research from the University of Torontos Centre for Cellular and Biomolecular Research has uncovered potential new explanations for these glaring differences. In comparing brain and heart tissue...Thu, 15 Nov 2007 12:00:00 AM GMThttp://www.eurekalert.org/pub_releases/2007-11/wjog-tmi111307.phpStone formation is an important feature of chronic pancreatitis, especially tropical calcific pancreatitis (TCP), where the stones are large in size, highly irregular in shape and cause enormous tissue destruction. The exact mechanism of stone formation is not well-understood. It is very important to understand the initial event so that stone formation can be controlled before it causes obstruction...Wed, 14 Nov 2007 12:00:00 AM GMThttp://www.eurekalert.org/pub_releases/2007-11/uoth-lgd110907.phpHOUSTON (Nov. 11, 2007)A research team led by scientists at The University of Texas Medical School at Houston has identified a defective gene that affects vascular smooth-muscle cells in people who suffer from hereditary thoracic aortic disease, which can kill victims with little warning in the prime of their lives.Thoracic aortic disease, specifically thoracic aortic aneurysms leading to aortic...Mon, 12 Nov 2007 12:00:00 AM GMThttp://www.eurekalert.org/pub_releases/2007-11/nyum-am110507.phpResearchers have discovered that a molecular switch in the protein making machinery of cells is linked to one of the most common forms of lethal breast cancer worldwide. The discovery by researchers at NYU School of Medicine could lead to new therapies for the cancer, called locally advanced breast cancer (LABC).Fri, 09 Nov 2007 12:00:00 AM GMThttp://www.healthsystem.virginia.edu/internet/news/archives07/diabetes_gene.cfmCHARLOTTESVILLE, Va., Nov. 6, 2007 - Researchers at the University of Virginia Health System have identified an enzyme thought to be an important instigator of the inner-body conflict that causes Type 1 diabetes. A chronic condition that affects nearly three million American children and adults, Type 1 diabetes is more severe than Type 2. Type 1 diabetes, also called autoimmune diabetes, arises when...Thu, 08 Nov 2007 12:00:00 AM GMThttp://www.reuters.com/article/healthNews/idUSN0644353620071107WASHINGTON (Reuters) - First, researchers grew enough fungus to give dandruff to 10 million people.Next, they sequenced its genes.Then they found out that not only does an icky fungus live on your head and cause dandruff-- but it could be having sex. On your head. Right now.Wed, 07 Nov 2007 12:00:00 AM GMThttp://www.aacr.org/home/about-us/news.aspx?d=920SINGAPORE -- Obesity is a well known risk factor for prostate, breast and colon cancer, but recent studies have shown that a protein responsible for generating fat cells also plays an important role in cancer. Researchers at the Genome Institute of Singapore have conducted, for the first time, a genome-wide analysis of how the protein, called perixosome proliferator-activated receptor gamma (PPARg...Wed, 07 Nov 2007 12:00:00 AM GMThttp://www.ohsu.edu/ohsuedu/newspub/releases/110607gene.cfmPORTLAND, Ore. Children who possess a gene known to increase the risk of Alzheimer's disease already show signs of reduced cognitive function, an Oregon Health & Science University study has found.Scientists in the OHSU School of Medicine discovered that 7- to 10-year-olds with a member of a family of genes implicated in development, nerve cell regeneration and neuroprotection display reduced...Wed, 07 Nov 2007 12:00:00 AM GMThttp://www.eurekalert.org/pub_releases/2007-11/plos-gep110207.phpResearchers at the Novartis Institute for Tropical Diseases and the Genome Institute of Singapore have identified new host genes associated with dengue virus infection, which may open new avenues to developing a drug to treat the disease.Dengue is the most prevalent mosquito-born viral disease affecting humans. Dengue-related disease results in an estimated 50-100 million cases of dengue fever...Wed, 07 Nov 2007 12:00:00 AM GMThttp://www.reuters.com/article/healthNews/idUSL0532649320071105LONDON (Reuters) - A very common gene can help explain why breast-fed babies tend to grow up to be more intelligent than those raised exclusively on bottled milk.Breast-fed babies who shared the genetic variant outscored bottle-fed peers in intelligence tests, researchers said. The variant to the FADS2 gene, involved in processing fatty acids, is found in about 90 percent of people, they added...Tue, 06 Nov 2007 12:00:00 AM GMThttp://www.genome.gov/26023566Bethesda, Md., Sunday, Nov. 4, 2007 An international team of scientists, supported in part by the National Human Genome Research Institute (NHGRI), one of the National Institutes of Health (NIH), today announced that its systematic effort to map the genomic changes underlying lung cancer has uncovered a critical gene alteration not previously linked to any form of cancer. The research, published...Mon, 05 Nov 2007 12:00:00 AM GMThttp://www.eurekalert.org/pub_releases/2007-11/uom-mri110207.phpUniversity of Manchester researchers have identified a genetic variant in a region on chromosome 6 that is associated with rheumatoid arthritis (RA), the most common inflammatory arthritis affecting 387,000 people in the UK.Professor Jane Worthington and her team at the Arthritis Research Campaign (arc) Epidemiology Unit at the University investigated 9 genetic regions identified earlier this year...Mon, 05 Nov 2007 12:00:00 AM GMThttp://www.bcm.edu/news/item.cfm?newsID=1006HOUSTON -- (November 4, 2007) -- Inheriting two genetic mutations that can individually cause epilepsy might actually be "seizure-protective," said Baylor College of Medicine researchers in a report that appears online today in the journal Nature Neuroscience."In the genetics of the brain, two wrongs can make a right," said Dr. Jeffrey L. Noebels, professor of neurology, neuroscience and molecular...Mon, 05 Nov 2007 12:00:00 AM GMThttp://www.upmc.com/Communications/MediaRelations/NewsReleaseArchives/2007/October/BrugadaGene.htmPITTSBURGH, October 31, 2007 Researchers at the University of Pittsburgh School of Medicine have identified a new gene responsible for a rare, inherited form of sudden cardiac arrest, known as Brugada syndrome. With the identification of this new gene, the researchers hope this will shed light on the more common forms of sudden death in patients with heart attacks and heart failure, and will help...Thu, 01 Nov 2007 12:00:00 AM GMThttp://med.stanford.edu/news_releases/2007/october/bioinformatics.htmlSTANFORD, Calif. Previously hidden obesity-related genes have been uncovered from old experiments by researchers at the Stanford University School of Medicine and Lucile Packard Childrens Hospital. The finding suggests that useful information about many medical disorders may be languishing in mountains of discarded data.Weve devised a fairly simple way to convert large amounts of existing...Fri, 26 Oct 2007 12:00:00 AM GMThttp://www.yale.edu/opa/newsr/07-10-25-03.all.htmlNew Haven, Conn. A study by researchers at the Yale Stem Cell Center for the first time demonstrates that piRNAs, a recently discovered class of tiny RNAs, play an important role in controlling gene function, it was reported this week in Nature.Haifan Lin, director of the stem cell center and professor of cell biology at Yale School of Medicine, heads the laboratory that originally identified...Fri, 26 Oct 2007 12:00:00 AM GMThttp://www.wellcome.ac.uk/doc_WTX041516.htmlThe genetics underlying late-onset Alzheimer's disease could soon be revealed thanks to a collaboration of leading UK experts. The team, led by scientists at Cardiff University, has received 1.3 million from the Wellcome Trust, the UK's largest medical research charity, to scan the entire human genome in search of the genes that predispose people to or protect them from developing the disease.Fri, 26 Oct 2007 12:00:00 AM GMThttp://www.newscientist.com/article/dn12813-genes-may-predict-disease-progression-in-aids.htmlVariation in two key genes can predict the course of an HIV-infected patients progression to AIDS, according to a new study.Until now, viral load the concentration of the HIV virus in the blood was thought to be the major predictor of how a person will fare against AIDS. But the new research suggests that cell-mediated immunity the way key immune cells respond to infection may be almost...Tue, 23 Oct 2007 12:00:00 AM GMThttp://publicaffairs.uth.tmc.edu/Media/newsreleases/nr2007/DisablingArthritis.htmHOUSTON(Oct. 22, 2007)Work done in part by researchers at The University of Texas Medical School at Houston has led to the discovery of two genes that cause ankylosing spondylitis, an inflammatory and potentially disabling disease. The findings are published in the Oct. 21 online edition of Nature Genetics, a journal that emphasizes research on the genetic basis for common and complex diseases.Mon, 22 Oct 2007 12:00:00 AM GMThttp://www.eurekalert.org/pub_releases/2007-10/wt-mgb101907.phpResearch funded by the Wellcome Trust and the Arthritis Research Campaign has identified two genes implicated in the disease ankylosing spondylitis, a common disease primarily causing back pain and progressive stiffness. The research, published online today in Nature Genetics, suggests that a treatment currently being trialled for Crohn's disease may also be applied to this disease.Mon, 22 Oct 2007 12:00:00 AM GMThttp://www.reuters.com/article/healthNews/idUSN1430909720071015WASHINGTON (Reuters) - Researchers have identified a batch of genes that not only prevent cancer but slow the aging process in worms, and say they are now looking to see if the genes have the same properties in humans.Many of the genes in the worms are already known to have counterparts in humans, and the team at the University of California, San Francisco, say they hope to better understand some...Mon, 15 Oct 2007 12:00:00 AM GMThttp://web.mit.edu/newsoffice/2007/cholesterol-1011.htmlMIT researchers have discovered a link between a gene believed to promote long lifespan and a pathway that flushes cholesterol from the body.The finding could help researchers create drugs that lower the risk of diseases associated with high cholesterol, including atherosclerosis (clogged arteries) and Alzheimer's disease.Fri, 12 Oct 2007 12:00:00 AM GMThttp://www.eurekalert.org/pub_releases/2007-10/uhoc-aob101107.phpResearchers from University Hospitals (UH) Ireland Cancer Center and Case Western Reserve University School of Medicine are part of a new national study that has analyzed more than 18,000 genes, including 5,000 previously unmapped genes, from breast and colorectal tumors. The study, published online by the journal Science on Oct. 11, shows a great number of genetic differences between breast and colon...Fri, 12 Oct 2007 12:00:00 AM GMThttp://www.nih.gov/news/pr/oct2007/nhgri-09.htmThe National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH), today announced grants totaling more than $80 million over the next four years to expand the ENCyclopedia Of DNA Elements (ENCODE) project, which in its pilot phase yielded provocative new insights into the organization and function of the human genome.Thu, 11 Oct 2007 12:00:00 AM GMThttp://wis-wander.weizmann.ac.il/site/en/weizman.asp?pi=371&doc_id=4890A group of Israeli scientists from the Technion Israel Institute of Technology, the Weizmann Institute of Science and Teva Pharmaceutical Industries have recently identified genes responsible for the positive response of many multiple sclerosis patients to the drug Copaxone. These findings may contribute to the development of personalized medicine for multiple sclerosis sufferers. Copaxone...Wed, 10 Oct 2007 12:00:00 AM GMThttp://www.cshl.edu/public/releases/07_new_genes.htmlCold Spring Harbor, NY Researchers at Cold Spring Harbor Laboratory (CSHL) have discovered three genes that interact with cancerous results in 20% of lung cancers. The three genes are located next to each other on human chromosome 14 and two are known to play key roles in fetal lung development. According to CSHL lead investigator David Mu, lung cancer cells in adults can reactivate genes that are...Tue, 09 Oct 2007 12:00:00 AM GMThttp://www.reuters.com/article/healthNews/idUSL084361320071008Two US scientists and their UK collaborator have been awarded the Nobel Prize for medicine for their groundbreaking work in gene technology.Mario Capecchi, Oliver Smithies and Briton Martin Evans developed a technique known as gene targeting. Mon, 08 Oct 2007 12:00:00 AM GMThttp://www.med.umich.edu/opm/newspage/2007/hmmr.htmANN ARBOR, Mich. Researchers in a multicenter international study have identified a new gene that, if mutated, may increase a womans risk of breast cancer by more than a third.Further, the researchers found that the gene, HMMR, interacts with the well-known breast cancer gene BRCA1. Alternations in either gene cause genetic instability and interfere with cell division, which could be a path...Mon, 08 Oct 2007 12:00:00 AM GMThttp://www.nih.gov/news/pr/oct2007/niams-04.htmResearchers in the United States and Sweden have identified a genetic region associated with increased risk of rheumatoid arthritis (RA), a chronic and debilitating inflammatory disease of the joints that affects an estimated 2.1 million Americans. The U.S. arm of the study involved a long-time collaboration between intramural researchers of the National Institute of Arthritis and Musculoskeletal and...Fri, 05 Oct 2007 12:00:00 AM GMThttp://www.reuters.com/article/healthNews/idUSN2937628820070930WASHINGTON (Reuters) - Smoking may turn on some genes in the body in a permanent and harmful way, scientists said on Thursday in a study that may help explain why the risk of cancer remains high even after smokers quit.They found many genetic changes that stop when a smoker quits, but found several genes that stay turned on for years, including several not previously linked with tobacco use.Mon, 01 Oct 2007 12:00:00 AM GMThttp://www.yale.edu/opa/newsr/07-09-27-02.all.htmlNew Haven, Conn. A study by Yale researchers offers a new view of what causes the greatest genetic variability among individuals suggesting that it is due less to single point mutations than to the presence of structural changes that cause extended segments of the human genome to be missing, rearranged or present in extra copies.Fri, 28 Sep 2007 12:00:00 AM GMThttp://www.ecco-org.eu/News/News/In-the-news/page.aspx/72?xf_itemId=112&xf_catId=8&xf_overviewPageIndex=2 Barcelona, Spain: Researchers in Portugal have discovered that a specific mutation of the COX2 gene seems to play a role in the onset of ovarian cancer, increasing womens susceptibility to developing the disease. The discovery raises the possibility that, if the findings are confirmed by further studies, it might be possible to use non-steroidal anti-inflammatory drugs (NSAIDs), such...Wed, 26 Sep 2007 12:00:00 AM GMThttp://www.eurekalert.org/pub_releases/2007-09/eecc-bcs092507.phpBarcelona, Spain: Researchers have found that the breast cancer susceptibility gene, BRCA1, plays a significant role in non-small cell lung cancer (NSCLC). Not only can it be used to predict outcome for patients with NSCLC, but it may also prove to be a valuable tool in choosing the best therapy for them.Dr Rafael Rosell today (Tuesday) told the European Cancer Conference (ECCO 14) in Barcelona...Tue, 25 Sep 2007 12:00:00 AM GMThttp://news.bbc.co.uk/2/hi/uk_news/scotland/north_east/7012269.stmBreast cancer patients could be spared unnecessary and lengthy treatment, according to new findings by researchers.Two genes that can identify which cells will respond to a common chemotherapy drug and which will not have been revealed by Aberdeen University staff. Tue, 25 Sep 2007 12:00:00 AM GMThttp://www.utsouthwestern.edu/utsw/cda/dept16498/files/412939.htmlDALLAS Sept. 21, 2007 Researchers at UT Southwestern Medical Center have found nearly 350 genes related to female fertility. Their research may open the door to much wider study in the poorly understood field of infertility.This study gives us a way to begin to understand the causes of female infertility, said Dr. Diego Castrillon, assistant professor of pathology and senior author of a study...Mon, 24 Sep 2007 12:00:00 AM GMThttp://144.92.105.154/14157New research in primates suggests that infants and children who carry a certain gene variant may be more vulnerable to the ill effects of fetal alcohol exposure.Reported online today (Sept. 21) in Biological Psychiatry, the findings represent the first evidence of a genetic risk for fetal alcohol spectrum disorder a condition that is characterized by profound mental retardation in its most severe...Mon, 24 Sep 2007 12:00:00 AM GMThttp://qnc.queensu.ca/story_loader.php?id=46efe3859c811Basic principles of biology rather than womens newfound economic independence can explain why fewer of them are getting married and having children, and why the trend may only be temporary, says a Queens researcher. Only in recent times have women acquired significant control over their own fertility, and many are preferring not to be saddled with the burden of raising children," says Lonnie...Mon, 24 Sep 2007 12:00:00 AM GMThttp://www.upmc.com/Communications/MediaRelations/NewsReleaseArchives/2007/September/GhedinBMalayi.htmPITTSBURGH, September 20, 2007 An international team of researchers has revealed the genetic secrets of one of the worlds most debilitating human parasites, Brugia malayi (B. malayi), which the World Health Organization estimates has seriously incapacitated and disfigured more than 40 million people around the globe. The study, which appears in the September 21 issue of the journal Science, reveals...Fri, 21 Sep 2007 12:00:00 AM GMT