BioSpace.com Featured News and Stories

Sugar Overload Can Damage Heart, University of Texas Health Science Center Study

Mon, 17 Jun 2013 12:00:00 AM GMT

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Too much sugar can set people down a pathway to heart failure, according to a study led by researchers at The University of Texas Health Science Center at Houston (UTHealth). A single small molecule, the glucose...

Merck & Co., Inc. to Cut Research Jobs as Sets Direction

Mon, 17 Jun 2013 12:00:00 AM GMT

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Merck & Co. (MRK), the second-largest U.S. drugmaker, plans to cut jobs at its research laboratories, two months after Roger Perlmutter took helm of the unit. The shakeup includes immediate elimination of some...

Psych Disorders Linked to Long-Term Memories Protein, Virginia Tech Study

Mon, 17 Jun 2013 12:00:00 AM GMT

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Researchers have discovered a pathway by which the brain controls a molecule critical to forming long-term memories and connected with bipolar disorder and schizophrenia. The discovery was made by a team of...

Johnson & Johnson to Buy Aragon Pharmaceuticals, Inc. for Up to $1 Billion

Mon, 17 Jun 2013 12:00:00 AM GMT

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Aragon Pharmaceuticals Announces Acquisition by Johnson & Johnson

SAN DIEGO, CA--(Marketwired - June 17, 2013) - Aragon Pharmaceuticals...

Metabolic Molecule Drives Growth of Aggressive Brain Cancer, Ohio State University and Study

Mon, 17 Jun 2013 12:00:00 AM GMT

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A study led by researchers at The Ohio State University Comprehensive Cancer Center -- Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC -- James) has identified an abnormal...

Norbrook Laboratories Launch Major Recruitment Drive for 400 New Jobs

Mon, 17 Jun 2013 12:00:00 AM GMT

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Norbrook is a leading manufacturer of veterinary pharmaceuticals and contract manufactures for all of the top pharmaceutical companies in the world at its three plants in Newry. In recent years the company has...

Gout Compound Linked to High BP in Kids, Study

Mon, 17 Jun 2013 12:00:00 AM GMT

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The gout culprit uric acid also appears to be an independent factor in high blood pressure among relatively high-risk children and teens, researchers found. Higher uric acid levels correlated with higher systolic...

Two Gene Variants May Predict Who Will Benefit From Breast Cancer Prevention Drugs, Mayo Clinic Study

Mon, 17 Jun 2013 12:00:00 AM GMT

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Researchers have identified two gene variants that may predict which women are likely to benefit from a long-term drug treatment that can cut the risk of developing the disease in half. The work represents...

Osteoporosis Drug Stops Growth Of Breast Cancer Cells, Even In Resistant Tumors, Study

Mon, 17 Jun 2013 12:00:00 AM GMT

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A drug approved in Europe to treat osteoporosis has now been shown to stop the growth of breast cancer cells, even in cancers that have become resistant to current targeted therapies, according to a Duke Cancer...

Depression in Postmenopausal Women May Increase Diabetes and Cardiovascular Disease Risk, University of Massachusetts Medical School Study

Mon, 17 Jun 2013 12:00:00 AM GMT

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Postmenopausal women who use antidepressant medication or suffer from depression might be more likely to have a higher body mass index (BMI), larger waist circumference and inflammation -- all associated with...

Teva Pharmaceutical Industries Limited Bags MicroDose Therapeutx (formerly MicroDose Technologies Inc) for $165 Million

Mon, 17 Jun 2013 12:00:00 AM GMT

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Teva Strengthens Respiratory Franchise with Acquisition of MicroDose Therapeutx

JERUSALEM--(BUSINESS WIRE)-- Teva Pharmaceutical Industries Ltd. (TEVA) today announced...

Obese Fathers Have Babies With High Body-Fat, Study

Mon, 17 Jun 2013 12:00:00 AM GMT

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Male mice who were fed a high-fat diet and became obese were more likely to father offspring who also had higher levels of body fat, a new Ohio University study finds. The effect was observed primarily in...

What Eli Lilly and Company's Cut Alzheimer's Drug Means for Merck & Co., Inc.

Mon, 17 Jun 2013 12:00:00 AM GMT

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Once again, Eli Lilly has suffered a setback trying to find a useful drug to combat Alzheimers. Last year, a pair of late-stage trials for an injectable drug called solanezumab failed to meet primary endpoints...

A Turbocharger for Nerve Cells, Study

Mon, 17 Jun 2013 12:00:00 AM GMT

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Locating a car that's blowing its horn in heavy traffic, channel-hopping between football and a thriller on TV without losing the plot, and not forgetting the start of a sentence by the time we have read to...

Perrigo Company Buys Fera Pharmaceuticals's Ophthalmic Product Portfolio for up to $129 Million

Mon, 17 Jun 2013 12:00:00 AM GMT

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Perrigo Company Acquires Ophthalmic Product Portfolio From Fera Pharmaceuticals, LLC For An Upfront Payment Of $93 Million

AstraZeneca PLC and NGM Biopharmaceuticals, Inc. Form Diabetes/Obesity Partnership

Mon, 17 Jun 2013 12:00:00 AM GMT

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AstraZeneca: MedImmune, AstraZenecas Biologics Arm, and NGM Biopharmaceuticals Announce Agreement to Discover and Develop Therapies for Diabetes and Obesity

SDERTLJE...

Novo Nordisk A/S Drops as New Eli Lilly and Company Drug Threatens Victoza

Mon, 17 Jun 2013 12:00:00 AM GMT

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Novo Nordisk A/S (NOVOB) fell the most among benchmark stocks in Copenhagen trading after Bank of America Merrill Lynch said the diabetes drug companys Victoza medicine faces a real threat from an Eli Lilly...

Sanofi (France)'s Animal Health Arm Seals Deal With

Mon, 17 Jun 2013 12:00:00 AM GMT

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The domestic animal health market just got more competitive, with one more multinational player -- drug-maker Sanofis animal health division Merial, sealing a deal in this segment. Merial had formalised an...

AOP Orphan Pharmaceuticals AG Spins Off Its Stake in Activartis Biotech GmbH and Outlines Business Strategy

Mon, 17 Jun 2013 12:00:00 AM GMT

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Vienna, Austria, June 17, 2013 / B3C newswire / - AOP Orphan Pharmaceuticals AG today announced the spin off of its 80 % stake in Activartis GmbH, a Vienna-based biotech company with a strong platform for immune...

Transition Therapeutics Inc. to Get $7 Million as Eli Lilly and Company to Assume Rights to TT-401

Mon, 17 Jun 2013 12:00:00 AM GMT

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Transition Therapeutics Announces Exercise of TT-401 Rights by Lilly

TORONTO, June 17, 2013 /PRNewswire/ - Transition Therapeutics...

Positive Survival Data for Bristol-Myers Squibb Company/AbbVie's Blood Cancer Drug

Mon, 17 Jun 2013 12:00:00 AM GMT
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Bristol-Myers Squibb and AbbVie Announce Progression-Free Survival Data from Phase 2 Open-Label Study of Investigational Agent Elotuzumab in Combination with Lenalidimide and Dexamethasone...

Workers of Puducherry Facility on Strike

Mon, 17 Jun 2013 12:00:00 AM GMT
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Drug firm Shasun Pharmaceuticals today said operations at its Puducherry facility have been affected due to strike by workers. A strike was resorted by the workers at the company's Puducherry facility that manufactures...

Janssen Research & Development's Ibrutinib Monotherapy Shows Efficacy in Patients With MCL or DLBCL

Mon, 17 Jun 2013 12:00:00 AM GMT
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Ibrutinib Phase 2 Data: Analyses Show Efficacy with Ibrutinib Monotherapy in Patients with Relapsed or Refractory Mantle Cell or Diffuse Large B-cell Lymphoma

RARITAN...

Royalty Pharma Hostile Bid for Elan Corporation PLC in Doubt After Vote

Mon, 17 Jun 2013 12:00:00 AM GMT
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Elan Announces Results of EGM

DUBLIN--(BUSINESS WIRE)--Jun. 17, 2013-- Elan Corporation, plc (NYSE:ELN) (Elan or the Company) announces that, at its Extraordinary General...

Changes Happening Inside Merck & Co., Inc.'s R&D

Fri, 14 Jun 2013 12:00:00 AM GMT
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I've heard from more than one source that Roger Perlmutter has been shaking things up this week at Merck. Since he only took over R&D in March, that's a pretty short lag time - if these reports are accurate...

Safety Fears Force Eli Lilly and Company to Halt Alzheimer's Trial

Fri, 14 Jun 2013 12:00:00 AM GMT
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Lilly Voluntarily Terminates Phase II Study for LY2886721, a Beta Secretase Inhibitor, Being Investigated as a Treatment for Alzheimer's Disease

INDIANAPOLIS, ...

Johnson & Johnson Sells Final Stake in Elan Corporation PLC for $332 Million

Fri, 14 Jun 2013 12:00:00 AM GMT
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Johnson & Johnson sold 25.4 million shares of Elan Corp., ending a relationship started four years ago to develop the Alzheimers disease drug bapineuzumab. J&J, based in New Brunswick, New Jersey, bought an...

AbbVie: We Can Win Race Against Gilead Sciences, Inc. for First New Hepatitis C Drugs

Fri, 14 Jun 2013 12:00:00 AM GMT
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AbbVie Inc. (ABBV) said it can win the race against Gilead Sciences Inc. (GILD) to bring to market a new generation of all-oral hepatitis C drugs. AbbVies trial for an unnamed multidrug therapy is in the last...

These Mutated Cystic Fibrosis Cells are Worth Billions to Vertex Pharmaceuticals (MA)

Fri, 14 Jun 2013 12:00:00 AM GMT
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This is my favorite data slide from Vertex Pharmaceuticals' (VRTX_) presentation at the European Cystic Fibrosis Society meeting. The slide is important because it helps explain how Vertex will dominate cystic...

Elan Corporation PLC Puts Itself Up for Sale

Fri, 14 Jun 2013 12:00:00 AM GMT
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Irish drug company Elan (ELN.I) said on Friday it will start a formal sale process in light of expressions of interest received to date. Royalty Pharma ROYPH.UL, which has made a hostile bid of up to $8 billion...

Mother's Age Tied to Risk of Delivery Complications, Trinity College Dublin Study

Fri, 14 Jun 2013 12:00:00 AM GMT
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Teenage mothers are at increased risk of delivering their babies prematurely, while older moms are more likely to give birth via Caesarean section, according to a new study from Ireland.

Help employers...

Hot Flash! Men May be the Cause of Menopause, McMaster University Study

Fri, 14 Jun 2013 12:00:00 AM GMT
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Ladies, here's one more thing you can blame on men: menopause. At least, that's according to a new theory.

Women go through menopause because men have consistently preferred younger women in recent...

Novartis AG Sacks 18 for Fabricating Sales Data

Fri, 14 Jun 2013 12:00:00 AM GMT
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Swiss drug maker Novartis AGs Indian subsidiary has run into trouble with some executives allegedly found to be inflating and presenting fabricated sales data for industry-leading dipeptidyl peptidase-4 (DPP...

Baldness Drug Curbs Men's Interest in Alcohol, George Washington University Study Suggests

Fri, 14 Jun 2013 12:00:00 AM GMT
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Some men who take the drug finasteride (Propecia) to slow a receding hair line may also find it reduces their interest in drinking alcohol, new research reveals.

Almost two-thirds of the men in the...

Biotech Conatus Pharmaceuticals Inc. Files for a $69 Million IPO

Fri, 14 Jun 2013 12:00:00 AM GMT
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Conatus Pharmaceuticals Inc. Files Registration Statement for Proposed Initial Public Offering

SAN DIEGO, June 14, 2013 /PRNewswire...

Deep Brain Stimulation Studied as Last-Ditch Obesity Treatment, Study

Fri, 14 Jun 2013 12:00:00 AM GMT
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The first use of deep brain stimulation to the brain's so-called "feeding center" -- the lateral hypothalamic area (LHA) -- was associated with a weight loss trend in morbidly obese patients whose stimulation...

CoMentis, Inc. and Announce Formation of a Joint Venture to Explore Nicotinic Modulators

Fri, 14 Jun 2013 12:00:00 AM GMT
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CoMentis and Anvyl Announce Formation of Alpharmagen, a Joint Venture to explore Nicotinic Modulators

SOUTH SAN FRANCISCO, Calif., June ...

Why Do Most Americans Avoid Clinical Trials?

Fri, 14 Jun 2013 12:00:00 AM GMT
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Despite increasing clamoring for new treatments, drugmakers regularly complain that enticing people in the US to enroll in clinical trials is not particularly easy. Often, the reasons given include a large percentage...

Gene Offers an Athlete's Heart Without the Exercise, Case Western Reserve University Study

Fri, 14 Jun 2013 12:00:00 AM GMT
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Researchers at Case Western Reserve University have found that a single gene poses a double threat to disease: Not only does it inhibit the growth and spread of breast tumors, but it also makes hearts healthier...

U.S. Doctors May Order Office Workers Out of Their Chairs, American Medical Association Reveals

Fri, 14 Jun 2013 12:00:00 AM GMT
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Sitting in front of a computer monitor all day may soon be officially against doctors advice.

The American Medical Association, which represents 225,000 doctors in the U.S. and recommends ways to...

Pittsburgh Life Sciences Greenhouse Cutting Jobs, Pay, Floor Space

Fri, 14 Jun 2013 12:00:00 AM GMT
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Pittsburgh Life Sciences Greenhouse Makes Significant Reductions Due to Uncertain Funding

PITTSBURGH, June 14, 2013 /PRNewswire/ ...

Pfizer Inc.'s Two New Top Pills Selling Slower Than Expected

Fri, 14 Jun 2013 12:00:00 AM GMT
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Pfizer Inc. (PFE)s touted two new drugs arent selling as fast as the company anticipated, a top executive said today, though the drugmaker expects the pills should still become blockbusters. Eliquis, a blood...

Amgen Shows Off Phase 3 Ovarian Cancer Data

Fri, 14 Jun 2013 12:00:00 AM GMT
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Amgen Announces Top-Line Results Of Phase 3 Trebananib (AMG 386) TRINOVA-1 Trial In Recurrent Ovarian Cancer

THOUSAND OAKS, Calif., June...

Mast Therapeutics (MSTX) Prices 50 Million Unit Offering

Fri, 14 Jun 2013 12:00:00 AM GMT
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Mast Therapeutics Prices Public Offering Of Units

SAN DIEGO, June 14, 2013 /PRNewswire/ -- Mast Therapeutics, Inc. (NYSE MKT: MSTX...

Genetics of Dyslexia and Language Impairment Unraveled, Yale University School Of Medicine Reveals

Fri, 14 Jun 2013 12:00:00 AM GMT
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A new study of the genetic origins of dyslexia and other learning disabilities could allow for earlier diagnoses and more successful interventions, according to researchers at Yale School of Medicine. Many students...

Celgene International S??rl's Apremilast Improves Oral Ulcer Pain From Behcet's Disease

Fri, 14 Jun 2013 12:00:00 AM GMT
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Oral Apremilast Achieves Statistical Significance for Primary and Secondary Endpoints in a Phase II Trial in Patients with Behets Disease

BOUDRY, Switzerland--(BUSINESS...

Cangene Corporation Withdraws MAA for Investigational Hemophilia Compound

Fri, 14 Jun 2013 12:00:00 AM GMT
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Cangene Announces Withdrawal of Marketing Authorization Application for Investigational Hemophilia Compound IB1001 in Europe

WINNIPEG , June 13, 2013 /CNW/ - Cangene Corporation...

Bristol-Myers Squibb Company, Simcere Pharmaceutical Group Form Pact for Development of RA Treatment

Fri, 14 Jun 2013 12:00:00 AM GMT
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Bristol-Myers Squibb and Simcere Enter Partnership to Co-Develop and Co-Commercialize Orencia SC (abatacept) in China

PRINCETON, N.J. & NANJING, China--(BUSINESS WIRE...

Restrictive Drug Laws Censor Science, Imperial College London and University of North Carolina Researchers Say

Thu, 13 Jun 2013 12:00:00 AM GMT
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The outlawing of drugs such as cannabis, magic mushrooms and other psychoactive substances amounts to scientific censorship and is hampering research into potentially important medicinal uses, leading scientists...

Elan Corporation PLC Boss Faces Ownership Showdown, Risks Losing $2 Billion if Royalty Pharma Walks

Thu, 13 Jun 2013 12:00:00 AM GMT
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When Kelly Martin, a former Merrill Lynch banker with no drug industry experience, took over as CEO of Ireland's Elan (ELN.I) in 2003, analysts assumed his mandate was to clean up the troubled company and sell...

Catalent Pharma Solutions to Add 90 Jobs in $35 Million Manufacturing Facility Expansion

Thu, 13 Jun 2013 12:00:00 AM GMT
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Catalent Pharma Solutions LLC will invest $35 million to expand its operations center and add 80,000 square feet to its current 100,000-square-foot facility on Enterprise Drive in Winchester, Kentucky, creating...

Another GlaxoSmithKline Scandal in China: Bribing Docs to Prescribe Meds?

Thu, 13 Jun 2013 12:00:00 AM GMT
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For the second time this month, GlaxoSmithKline is embroiled in scandal in China. In this instance, the drugmaker is investigating allegations that its sales staff there was involved in bribing doctors to prescribe...

GlaxoSmithKline???s MS Drug Tests Put on Hold After Fraud Claim

Thu, 13 Jun 2013 12:00:00 AM GMT
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GSK has paused a Phase I trial of an MS drug and fired its China R&D chief, Jingwu Zhang, after finding 'manipulated' data in a paper published in Nature Medicine in 2010 .

Help employers find you...

Why Saliva of Adults Help Fight Bird Flu Better, /i> Reveals

Thu, 13 Jun 2013 12:00:00 AM GMT
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Spit. Drool. Dribble. Saliva is not normally a topic of polite conversation, but it may be the key to explaining the age and sex bias exhibited by influenza and other diseases, according to a new study. Published...

Sanofi (France) Linked to Insider Trading Claims

Thu, 13 Jun 2013 12:00:00 AM GMT
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The Securities and Exchange Commission filed civil complaints against two brothers on Tuesday, alleging that Andrew W. Jacobs and his brother Leslie J. Jacobs II traded on inside information about a tender offer...

Gilead Sciences, Inc.'s Viread Reduces HIV Risk for Drug Users in Study

Thu, 13 Jun 2013 12:00:00 AM GMT
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Gilead Sciences Inc. (GILD)s Viread pill reduced the risk of injected-drug users contracting the AIDS virus by half in a study in Thailand, a finding that may give public health officials a new weapon to fight...

Even Babies Prefer the Underdog, Kyoto University and Study

Thu, 13 Jun 2013 12:00:00 AM GMT
The human brain may be wired to sympathize with the underdog. Even if the underdog is a yellow square being chased by a blue circle, and the brain has been checking out the outside world for only 10 months.

A Japanese research team found that 16 of 20 infants reached for the pursued yellow square rather than the aggressive blue ball as the ball bumped the square seven times, then smashed...

Eli Lilly and Company, Incyte Corporation Arthritis Pill Effective in Mid-Stage Study

Thu, 13 Jun 2013 12:00:00 AM GMT
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Lilly and Incyte Announce Baricitinib Efficacy and Safety Data from the Open-Label, Long-Term Extension of the Phase 2b JADA Study in Patients with Rheumatoid Arthritis

Pesticide Exposure Tied to Fetal-Movement Changes, Johns Hopkins University Study

Thu, 13 Jun 2013 12:00:00 AM GMT
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WEDNESDAY, June 12 (HealthDay News) -- A pregnant woman's exposure to environmental contaminants affects her unborn baby's heart rate and movement, a new study says.

"Both fetal motor activity and...

Spiritual People More Likely to Commit Crimes Than Atheists, Baylor University Study Reveals

Thu, 13 Jun 2013 12:00:00 AM GMT
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Young adults who deem themselves "spiritual but not religious" are more likely to commit property crimes -- and to a lesser extent, violent ones -- than those who identify themselves as either "religious and...

Repeat Offender: Baxter Healthcare Corporation, the FDA and Too Much Mold to Count

Thu, 13 Jun 2013 12:00:00 AM GMT
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As the FDA continues its push to crack down on manufacturing violations, warning letters have become standard fare. But every so often, a missive stands out from the crowd thanks to the sort of violations that...

Zydus Pharmaceuticals (USA) Inc. to Recall Single Lot of Warfarin After Complaints

Thu, 13 Jun 2013 12:00:00 AM GMT
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Zydus Pharmaceuticals USA Inc. Issues Voluntary Nationwide Recall of Warfarin 2 mg Tablets, Lot MM5767, Expiration Date June 2014, Due to Oversized Tablets

PENNINGTON...

Men With Restless Legs May Die Early, Brigham and Women's Hospital Study

Thu, 13 Jun 2013 12:00:00 AM GMT
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A new study from the US finds that men with restless legs syndrome (RLS) may have a 39% increased risk of dying earlier compared to men without the condition, which is characterized by an irresistible urge to...

Food-Packaging Chemical Linked to Obesity in Girls, Kaiser Permanente Study

Thu, 13 Jun 2013 12:00:00 AM GMT
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Poor diet and lack of exercise might not be the only factors contributing to the obesity epidemic. A new study suggests the environment may also play a role.

Eating too much and exercising too little...

Cocoa May Help Fight Diabetes, Inflammation, Penn State University Study

Thu, 13 Jun 2013 12:00:00 AM GMT
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A few cups of hot cocoa may not only fight off the chill of a winter's day, but they could also help obese people better control inflammation-related diseases, such as diabetes, according to Penn State researchers...

Teva Pharmaceutical Industries Limited Victim of Product Tampering - Report

Thu, 13 Jun 2013 12:00:00 AM GMT
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Regulators in France have reported the first findings of an investigation into Teva Pharmceutical after some zopiclone sleeping pills were found in packs of the diuretic furosemide.The country's National...

Using Frugal Business Model, Orphagen Pharmaceuticals Targets Orphan Receptors

Thu, 13 Jun 2013 12:00:00 AM GMT
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The decline of venture capital investments in life sciences startups has provoked a lot of angst in the U.S., with many experts predicting a shortage of new drugs for the pharmaceutical product pipeline. Life...

FDA Approves Amgen's Xgeva to Treat Giant Cell Tumor of the Bone

Thu, 13 Jun 2013 12:00:00 AM GMT
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FDA approves Xgeva to treat giant cell tumor of the bone

June 13, 2013 -- The U.S. Food and Drug Administration today expanded the approved use of Xgeva (denosumab) to...

Better Athletes Have More Heart Arrhythmias, Uppsala University Hospital Study

Thu, 13 Jun 2013 12:00:00 AM GMT
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PROBLEM: Extreme endurance athletes, like long-distance runners, bikers, and even cross-country skiers, tend to have enlarged hearts. Also known as "Athlete's Heart," the condition may be associated with an...

PRISM Pharma Closes $15 Million Series C Financing

Thu, 13 Jun 2013 12:00:00 AM GMT
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PRISM Pharma Closes $15 million Series C Financing to Advance PRI-724 into Non-oncology Indications

YOKOHAMA, Japan, June 13, 2013

Obese Women Risk Delivering Baby Early, Karolinska Institute Study

Wed, 12 Jun 2013 12:00:00 AM GMT
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Pregnant women who are overweight or obese are more likely to give birth prematurely, according to a new study from Sweden.

Researchers found that link was strongest for babies born the earliest ...

Childhood Cancer's Health Woes Persist for Years, St. Jude Children's Research Hospital Study

Wed, 12 Jun 2013 12:00:00 AM GMT
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A study of over 1,700 childhood cancer survivors found that 98% of the participants had at least one chronic disease such as new cancers, heart disease or abnormal lung function.

The research, published...

GlaxoSmithKline Fires Head of Its Chinese R&D Unit for Data Fraud

Wed, 12 Jun 2013 12:00:00 AM GMT
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After conducting an internal investigation, GlaxoSmithKline has determined that a scientific paper that was published in Nature Medicine contained fabricated data and has dismissed Jingwu Zang, one of the listed...

Teva Pharmaceutical Industries Limited, Sun Pharmaceutical Industries Ltd to Pay $2.15 Billion to Settle Pfizer Inc. Patent Suit

Wed, 12 Jun 2013 12:00:00 AM GMT
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Pfizer Inc said Teva Pharmaceuticals Industries Ltd and Sun Pharmaceutical Industries Ltd would pay $2.15 billion to settle a patent infringement lawsuit related to its acid-reflux drug Protonix.Japan's...

Cytokinetics, Inc., Amgen Expand $75 Million Development Deal Into Japan

Wed, 12 Jun 2013 12:00:00 AM GMT
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Amgen and Cytokinetics Announce Expansion of License for Omecamtiv Mecarbil

THOUSAND OAKS, Calif. AND SOUTH SAN FRANCISCO, Calif, (June 12, 2013) - Amgen (AMGN) and Cytokinetics...

Bristol-Myers Squibb Company's Orencia Matches Abbott Laboratories' Humira in Arthritis Study

Wed, 12 Jun 2013 12:00:00 AM GMT
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ORENCIA (abatacept) Shows Comparable Efficacy to Humira (adalimumab) in Year Two Data from Head-to-Head Study in Patients with Moderate to Severe Rheumatoid Arthritis

Worried About Diabetes? Walk After Every Meal, George Washington University Suggests

Wed, 12 Jun 2013 12:00:00 AM GMT
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If you're at risk for developing type 2 diabetes, then take a 15-minute walk after every meal.

A study, out today, shows that moderately-paced walks after meals work as well at regulating overall...

Merck & Co., Inc. Joins Novo Nordisk A/S to Reassure Safety of Diabetes Drugs

Wed, 12 Jun 2013 12:00:00 AM GMT
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Merck & Co. (MRK), Novo Nordisk A/S (NOVOB) and other makers of diabetes treatments may be asked to collect more data on a potential cancer link even as they try to reassure U.S. regulators this week of the...

1 in 20 Washes Hands Properly After Using a Restroom, Michigan State University Study

Wed, 12 Jun 2013 12:00:00 AM GMT
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Did you wash your hands properly after you used the toilet? Probably not, a new study suggests.

Researchers discreetly watched 3,749 people, 60 percent of them women, after they used public toilets...

Eyeball Discovery May Mean Safer Surgery, University of Nottingham Study

Wed, 12 Jun 2013 12:00:00 AM GMT
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Scientists at The University of Nottingham have discovered a previously undetected layer in the cornea, the clear window at the front of the human eye.

The breakthrough, announced in a study published...

Inhaled Chemo Kills More Lung Tumors, Rutgers University Study

Wed, 12 Jun 2013 12:00:00 AM GMT
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Lung cancer kills about 1.5 million men and women around the world more than the number of people who die from breast, colon, pancreatic and prostate cancers combined.

This happens, in part, because...

Yoga May Help Boost Brain Power Better Than Aerobic Exercise, Wayne State University Study

Wed, 12 Jun 2013 12:00:00 AM GMT
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Doing yoga for as little as 20 minutes may be able to boost your brain power.

Subjects who participated in a single yoga session had better speed and accuracy scores on working memory and inhibitory...

Body Clocks Linked to Osteoarthritis, University of Manchester Study

Wed, 12 Jun 2013 12:00:00 AM GMT
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Scheduled exercise, regular meals and the periodic warming and cooling of joints could be used to relieve the symptoms of osteoarthritis according to scientists at The University of Manchester. Their research...

Dezima Pharma Appoints Seasoned New CEO

Wed, 12 Jun 2013 12:00:00 AM GMT
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Dezima Pharma Appoints Seasoned New CEO

NAARDEN, The Netherlands--(BUSINESS WIRE)-- Dezima Pharma (Dezima), the biotechnology company developing innovative drugs in...

NeuroVive Pharmaceutical AB Signs $7.6 Million JV With

Wed, 12 Jun 2013 12:00:00 AM GMT
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NeuroVive Pharmaceutical: NeuroVive signs collaboration agreement with Isomerase Therapeutics and receives the first milestone payment from Sihuan

STOCKHOLM--(BUSINESS...

Why We Should Spend More on Pricey Cancer Drugs

Tue, 11 Jun 2013 12:00:00 AM GMT
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Heres a heretical statement: We dont spend enough money on high-priced cancer drugs.

In recent months, there have been provocative editorials by leading academic cancer doctors arguing that the...

Former Bristol-Myers Squibb Company Executive Admits to Insider Trading

Tue, 11 Jun 2013 12:00:00 AM GMT
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A former Bristol-Myers Squibb Co (BMY.N) finance executive on Monday pleaded guilty to an insider trading charge, admitting to buying stock options in a biotechnology company that the drugmaker was preparing...

Almac Group Announces Further Expansion and 229 New Jobs

Tue, 11 Jun 2013 12:00:00 AM GMT
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ALMAC ANNOUNCES FURTHER EXPANSION AND 229 NEW JOBS

11th June 2013 -- Following the success of one of its key client partnered products, Craigavon-based pharmaceutical...

Brain Circuits Link OCD Behavior and Obesity, University of Iowa Study

Tue, 11 Jun 2013 12:00:00 AM GMT
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What started as an experiment to probe brain circuits involved in compulsive behavior has revealed a surprising connection with obesity.

The University of Iowa-led researchers bred mice missing a...

Did You Know the GlaxoSmithKline US HQ is Really a Sublet 10-By-10 Foot Office?

Tue, 11 Jun 2013 12:00:00 AM GMT
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Get ready for a trick question. GlaxoSmithKline has US operations based largely in Philadelphia, where some 1,800 people work in 650,000 square feet of office space. Then, there is a 10-by-10 foot sublet office...

Gonorrhea Drug Resistance Recedes With New Drug Combo Approach, Lancet Study Reveals

Tue, 11 Jun 2013 12:00:00 AM GMT
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Drug-resistant gonorrhea receded in the U.K. as doctors switched to a new combination of antibiotics to clear the sexually transmitted bacterium, a study found.

Analysis of more than 6,000 samples...

Agios Pharmaceuticals Files for $86 Million IPO

Tue, 11 Jun 2013 12:00:00 AM GMT
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Biopharmaceutical company Agios Pharmaceuticals Inc filed with U.S. regulators on Monday to raise up to $86 million in an initial public offering of common stock.The Cambridge, Massachusetts-based company...

Questcor Pharmaceuticals, Inc. (Headquarters) Acquires Rights to Synacthen From Novartis AG for Up $135 Million

Tue, 11 Jun 2013 12:00:00 AM GMT
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Questcor Pharmaceuticals Acquires Rights to Synacthen

ANAHEIM, Calif., June 11, 2013 /PRNewswire/ -- Questcor Pharmaceuticals, Inc...

AstraZeneca PLC in Deal for Pearl Therapeutics Worth Up to $1.15 Billion

Tue, 11 Jun 2013 12:00:00 AM GMT
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AstraZeneca to acquire Pearl Therapeutics to strengthen respiratory portfolio

Monday, 10 June 2013 -- AstraZeneca announced today that it has entered into a definitive...

Epigenetic Factor Likely Plays a Key Role in Fueling Most Common Childhood Cancer, St. Jude Children's Research Hospital Study

Tue, 11 Jun 2013 12:00:00 AM GMT
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MEMPHIS, Tenn., June 10, 2013 /PRNewswire-USNewswire/ --Changes in an epigenetic mechanism that...

Dermira Raises $35 Million

Tue, 11 Jun 2013 12:00:00 AM GMT
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Dermira Raises $35m to Fund Innovation in Dermatology

REDWOOD CITY, Calif.--(BUSINESS WIRE)-- Dermira, a development-stage biotechnology company focused on developing...

"Suspicious" Death in France After Teva Pharmaceutical Industries Limited Medicine Alert

Tue, 11 Jun 2013 12:00:00 AM GMT
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French police are investigating the death of a 92-year-old man as "suspicious" after he was given medicine that may have been wrongly labelled as a diuretic drug, a police representative said on Sunday.The...

Hey, Fellas, Olive Oil and Nuts Tied to Prostate Cancer Survival, University of California, San Francisco (UCSF) Study

Tue, 11 Jun 2013 12:00:00 AM GMT
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Sometimes, it doesn't take a major diet overhaul to get significant health benefits. Small changes can be helpful, too.

This seems to be the take-home message from a new study in JAMA Internal Medicine...

NovoBioPharma, Partnership of Top Life Science Experts, Launches

Tue, 11 Jun 2013 12:00:00 AM GMT
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CAMBRIDGE, Mass., June 11, 2013 /PRNewswire/ --NovoBioPharma...

Obama Administration Reverses Course on Teva Pharmaceutical Industries Limited's Plan B Pill

Tue, 11 Jun 2013 12:00:00 AM GMT
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The Obama administration will scrap age restrictions on the sale of emergency contraception pills, making the morning-after pill available to women and girls without a prescription.

Help employers...

CT Scans in Children May Trigger 5,000 Cancers, /i> Study Shows

Tue, 11 Jun 2013 12:00:00 AM GMT
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The radiation from 4 million annual computerized tomography scans in U.S. children younger than 15 may lead to almost 5,000 cancers each year in the future, a study found.

The use of CT scans of the...

PDL BioPharma, Inc. Files for Arbitration Against Genentech Based on Underpayment of Royalties

Tue, 11 Jun 2013 12:00:00 AM GMT
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PDL Files for Arbitration Against Genentech Based on Underpayment of Royalties

INCLINE VILLAGE, Nev., June 11, 2013 /PRNewswire/ ...

Debt-Ridden Elder Pharmaceutical Ltd. Up for Sale

Tue, 11 Jun 2013 12:00:00 AM GMT
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Mumbai-based pharmaceutical company Elder PharmaceuticalsBSE -0.57 % has been put on the block as it grapples with mounting debts and rising competition in the pharmaceutical industry.The company, founded...

Low Diastolic Pressure Linked to Brain Atrophy, University Medical Center Utrecht Study

Tue, 11 Jun 2013 12:00:00 AM GMT
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Low baseline diastolic blood pressure (DBP) appears to be associated with brain atrophy in patients with arterial disease, whenever declining levels of blood pressure (BP) over time among patients who had a...

GlaxoSmithKline Probes Allegedly Fraudulent Data in Study Written by Employees

Tue, 11 Jun 2013 12:00:00 AM GMT
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In the latest instance in which a global drugmaker has become embroiled in a scandal over published study results, GlaxoSmithKline is investigating whether a paper that appeared in Nature Medicine three years...

Valeant Pharmaceuticals International Abandons Bid for Serbia's

Tue, 11 Jun 2013 12:00:00 AM GMT
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Canada's Valeant (VRX.TO) has pulled out of a possible bid for a Serbian drug company in the wake of its $8.7 billion purchase of contact lenses maker Bausch & Lomb.Citing last month's acquisition deal...

Lack of Vitamin D Linked to Hypertension, University College London Study

Tue, 11 Jun 2013 12:00:00 AM GMT
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A large-scale genetic study involving over 155,000 individuals has enabled researchers to discover the causal link between hypertension and vitamin D deficiency. The results provide a strong case for food fortification...

Common Genetic Disease Linked to Father's Age, University of Southern California Study

Tue, 11 Jun 2013 12:00:00 AM GMT
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Scientists at USC have unlocked the mystery of why new cases of the genetic disease Noonan syndrome are so common a mutation that causes the disease disproportionately increases a normal fathers production...

Sanofi (France) MS Drug Nears Green Light After Pass-the-Parcel Marathon

Tue, 11 Jun 2013 12:00:00 AM GMT
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One of the world's longest running drug development sagas may draw to a close this month as French firm Sanofi hopes for a European green light for its new multiple sclerosis medicine Lemtrada.The drug...

Roche Backs Out on Seaside Therapeutics Drug Trial for Fragile X. Parents Dismayed

Tue, 11 Jun 2013 12:00:00 AM GMT
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Most pharmaceuticals represent years of research, millions of dollars of investment, and the tacit promise made by the government that what is in the bottle is safe and effective.Most pharmaceuticals also...

FDA Rejects AVEO Oncology (Formerly known as AVEO Pharmaceuticals, Inc.)'s Kidney Cancer Drug, Asks for Additional Trial

Tue, 11 Jun 2013 12:00:00 AM GMT
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AVEO Announces Complete Response Letter Received for Tivozanib New Drug Application in Renal Cell Carcinoma

CAMBRIDGE, Mass.--(BUSINESS WIRE)--June 10, 2013 -- AVEO Oncology...

Anger and Heart Attacks Strongly Linked, Harvard Medical School Study

Tue, 11 Jun 2013 12:00:00 AM GMT
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A study from Harvard Medical School researchers shows that the risk of having a heart attack is significantly higher following an outburst of anger the more intense the outburst, the higher the risk....

Diabetes Drug Shows Promise in Treatment of Neurodegenerative Disease, Study

Tue, 11 Jun 2013 12:00:00 AM GMT
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Researchers in Spain have found that a drug used to control Type II diabetes can help repair the spinal cords of mice suffering from the inherited disease adrenoleukodystrophy which, untreated, leads eventually...

Vegetable Oil is Good for You, University of Missouri and University of Illinois Study

Tue, 11 Jun 2013 12:00:00 AM GMT
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A typical American consumes approximately 3 or more tablespoons of vegetable oil each day. Vegetable oils, like those from soy, corn and canola, are a significant source of calories and are rich in linoleic...

Elan Corporation PLC Board Rejects $6.7 Billion Royalty Pharma Offer

Tue, 11 Jun 2013 12:00:00 AM GMT
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Elan Board Of Directors Unanimously And Without Reservation Rejects Royalty Pharma's Revised Tender Offer

DUBLIN--(BUSINESS WIRE)--Jun. 10, 2013-- Elan Corporation, plc...

Abbott Laboratories Doubled Niaspan U.S. Sales Before Trials Cut Use

Tue, 11 Jun 2013 12:00:00 AM GMT
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Abbott Laboratories (ABT) aggressively promoted its Niaspan cholesterol treatment, almost tripling U.S. use of the medication, in the seven-year period before studies in 2011 found the drug ineffective, a study...

Shire plc Ups Headcount Despite Takeover Rumors

Mon, 10 Jun 2013 12:00:00 AM GMT
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Flemming Ornskov, who took over as Shire Plc (SHP)s chief executive officer six weeks ago, is adding sales jobs and eschewing future share buybacks while cooling speculation that the drugmaker is an imminent...

FDA Asks for More Safety Data on Dynavax Technologies Corporation's Hepatitis B Vaccine; Stock Drops -0.95(38.46%) @ 1:30PM EDT

Mon, 10 Jun 2013 12:00:00 AM GMT
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Dynavax Reports Feedback From FDA Meeting Regarding HEPLISAV(TM) Biologic License Application

BERKELEY, CA--(Marketwired - June 10, 201...

Interferon-Beta Aids Balance and Movement in Mice With Spinocerebellar Ataxia 7, Study

Mon, 10 Jun 2013 12:00:00 AM GMT
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The first in vivo trial of the use of interferon-beta in a mouse model of the group of fatal diseases known as spinocerebellar ataxia has shown that its use can significantly improve their physical condition...

BioLineRx Ltd. Signs a $30 Million Hepatitis Deal With a Leading Chinese Company

Mon, 10 Jun 2013 12:00:00 AM GMT
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BioLineRx Enters into Collaboration to Develop and Commercialize Hepatitis C Drug with CTTQ, Leading Chinese Pharma Company for Liver Disease Therapeutics

JERUSALEM-...

FDA Approves Sanofi Pasteur Influenza Vaccine

Mon, 10 Jun 2013 12:00:00 AM GMT
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New Four-Strain Influenza Vaccine from Sanofi Pasteur Now Licensed By FDA for Broad Age Range of Children and Adults

LYON, France, June ...

New Cause of Life-Threatening Disease Identified, University of Copenhagen Study

Mon, 10 Jun 2013 12:00:00 AM GMT
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Danish researchers have just published findings that explain a previously unknown mechanism used by cells to communicate with one another. The research significantly contributes to understanding why some...

GlaxoSmithKline's Avandia Vote Ends an Era of Drug Safety Scandals

Mon, 10 Jun 2013 12:00:00 AM GMT
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Avandia, once the most-used diabetes pill on the planet, was all but finished. After concerns emerged that it might cause heart attacks, the Food and Drug Administration in 2010 put severe restrictions on Avandia...

Less Than 6 Hours of Sleep Ups a Woman's Heart Attack Risk, University of Surrey Study

Mon, 10 Jun 2013 12:00:00 AM GMT
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Getting too little sleep for several nights in a row disrupts hundreds of genes that are essential for good health, including those linked to stress and fighting disease. Tests on people who slept less than...

Sanofi (France) Steps Up Diabetes Drive as Rivals Raise the Stakes

Mon, 10 Jun 2013 12:00:00 AM GMT
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In a leafy suburb of Frankfurt, a state-of-the-art plant churns out up to 1 million insulin pens every day in French drugmaker Sanofi's drive to keep its no. 2 spot in the $43 billion-a-year diabetes market...

BioSpace.com Featured News and Stories

Sugar Overload Can Damage Heart, University of Texas Health Science Center Study

Merck & Co., Inc. to Cut Research Jobs as Sets Direction

Psych Disorders Linked to Long-Term Memories Protein, Virginia Tech Study

Johnson & Johnson to Buy Aragon Pharmaceuticals, Inc. for Up to $1 Billion

Metabolic Molecule Drives Growth of Aggressive Brain Cancer, Ohio State University and Study

Norbrook Laboratories Launch Major Recruitment Drive for 400 New Jobs

Gout Compound Linked to High BP in Kids, Study

Two Gene Variants May Predict Who Will Benefit From Breast Cancer Prevention Drugs, Mayo Clinic Study

Osteoporosis Drug Stops Growth Of Breast Cancer Cells, Even In Resistant Tumors, Study

Depression in Postmenopausal Women May Increase Diabetes and Cardiovascular Disease Risk, University of Massachusetts Medical School Study

Teva Pharmaceutical Industries Limited Bags MicroDose Therapeutx (formerly MicroDose Technologies Inc) for $165 Million

Obese Fathers Have Babies With High Body-Fat, Study

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A Turbocharger for Nerve Cells, Study

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AstraZeneca PLC and NGM Biopharmaceuticals, Inc. Form Diabetes/Obesity Partnership

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Sanofi (France)'s Animal Health Arm Seals Deal With

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Workers of Puducherry Facility on Strike

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Royalty Pharma Hostile Bid for Elan Corporation PLC in Doubt After Vote

Changes Happening Inside Merck & Co., Inc.'s R&D

Safety Fears Force Eli Lilly and Company to Halt Alzheimer's Trial

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These Mutated Cystic Fibrosis Cells are Worth Billions to Vertex Pharmaceuticals (MA)

Elan Corporation PLC Puts Itself Up for Sale

Mother's Age Tied to Risk of Delivery Complications, Trinity College Dublin Study

Hot Flash! Men May be the Cause of Menopause, McMaster University Study

Novartis AG Sacks 18 for Fabricating Sales Data

Baldness Drug Curbs Men's Interest in Alcohol, George Washington University Study Suggests

Biotech Conatus Pharmaceuticals Inc. Files for a $69 Million IPO

Deep Brain Stimulation Studied as Last-Ditch Obesity Treatment, Study

CoMentis, Inc. and Announce Formation of a Joint Venture to Explore Nicotinic Modulators

Why Do Most Americans Avoid Clinical Trials?

Gene Offers an Athlete's Heart Without the Exercise, Case Western Reserve University Study

U.S. Doctors May Order Office Workers Out of Their Chairs, American Medical Association Reveals

Pittsburgh Life Sciences Greenhouse Cutting Jobs, Pay, Floor Space

Pfizer Inc.'s Two New Top Pills Selling Slower Than Expected

Amgen Shows Off Phase 3 Ovarian Cancer Data

Mast Therapeutics (MSTX) Prices 50 Million Unit Offering

Genetics of Dyslexia and Language Impairment Unraveled, Yale University School Of Medicine Reveals

Celgene International S??rl's Apremilast Improves Oral Ulcer Pain From Behcet's Disease

Cangene Corporation Withdraws MAA for Investigational Hemophilia Compound

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Restrictive Drug Laws Censor Science, Imperial College London and University of North Carolina Researchers Say

Elan Corporation PLC Boss Faces Ownership Showdown, Risks Losing $2 Billion if Royalty Pharma Walks

Catalent Pharma Solutions to Add 90 Jobs in $35 Million Manufacturing Facility Expansion

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GlaxoSmithKline???s MS Drug Tests Put on Hold After Fraud Claim

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Even Babies Prefer the Underdog, Kyoto University and Study

Eli Lilly and Company, Incyte Corporation Arthritis Pill Effective in Mid-Stage Study

Pesticide Exposure Tied to Fetal-Movement Changes, Johns Hopkins University Study

Spiritual People More Likely to Commit Crimes Than Atheists, Baylor University Study Reveals

Repeat Offender: Baxter Healthcare Corporation, the FDA and Too Much Mold to Count

Zydus Pharmaceuticals (USA) Inc. to Recall Single Lot of Warfarin After Complaints

Men With Restless Legs May Die Early, Brigham and Women's Hospital Study

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Cocoa May Help Fight Diabetes, Inflammation, Penn State University Study

Teva Pharmaceutical Industries Limited Victim of Product Tampering - Report

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Better Athletes Have More Heart Arrhythmias, Uppsala University Hospital Study

PRISM Pharma Closes $15 Million Series C Financing

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Childhood Cancer's Health Woes Persist for Years, St. Jude Children's Research Hospital Study

GlaxoSmithKline Fires Head of Its Chinese R&D Unit for Data Fraud

Teva Pharmaceutical Industries Limited, Sun Pharmaceutical Industries Ltd to Pay $2.15 Billion to Settle Pfizer Inc. Patent Suit

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Bristol-Myers Squibb Company's Orencia Matches Abbott Laboratories' Humira in Arthritis Study

Worried About Diabetes? Walk After Every Meal, George Washington University Suggests

Merck & Co., Inc. Joins Novo Nordisk A/S to Reassure Safety of Diabetes Drugs

1 in 20 Washes Hands Properly After Using a Restroom, Michigan State University Study